Meta-analyses showed reductions in the absolute risk of 0.8% (95% CI, 0.4%-1.2%) for all-cause mortality, 1.3% (95% CI, 0.9%-1.7%) for myocardial infarction, and 0.4% (95% CI, 0.2%-0.6%) for stroke in those randomized to treatment with statins,
Comment: This study shows that in elderly patients, higher LDL/”bad” cholesterol is associated with longer lifespan. Summary: Clinical Bottom Line This systematic review presents a provocative challenge to the conventional cholesterol hypothesis. In an analysis of cohort studies including over 68,000 individuals older than 60, high low-density lipoprotein cholesterol (LDL-C) was not associated with increased […]
Comment: Another in a line of studies showing that our concept of cholesterol is wrong when it comes to the outcomes that matter. This one is particularly interesting as it breaks it down by age, showing that as we get older, higher cholesterol becomes more protective. Summary: Based on this large observational study, the health […]
Comment: Although this doesn’t negate the potential of increased risk of atrial fibrillation seen in other studies, a lower rate of death seems more important. Summary: Clinical Bottom Line This large cohort study shows a modest association between habitual fish oil use and a lower risk of all-cause mortality. However, it is not possible to […]
