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OncWonk – Oncology Research Reviews
OncWonk – Oncology Research Reviews
Revolutionizing Naturopathic Oncology Research for Healthcare Professionals Contact Us for a complimentary 1 month trial. Introducing OncWonk, the groundbreaking AI-assisted Naturopathic Oncology Database meticulously curated to empower healthcare professionals with unparalleled access to cutting-edge research. This exclusive platform houses an expansive collection of nearly 120,000 articles from the medical literature dedicated to the exploration and […]
Comment: The findings in this randomized controlled trial of 5,804 elderly participants are unequivocal: after a mean follow-up of 42 months, pravastatin demonstrated absolutely no difference in cognitive decline across any domain—including executive function, processing speed, or memory. It also celebrates a 24% RRR in cardiovascular mortality while the Absolute Risk Reduction (ARR) was a […]
Comment: This is another in a long line of studies where a randomized trial fails to show the benefit seen in observational cohorts. It is crucial to prioritize hard, randomized data because it is the only way to strip away the Healthy User Bias that plagues nutritional and pharmaceutical research. In observational studies, people who […]
Comment: Although meta-analyses are considered to be a higher level method, there are significant issues with them. I am always suspicious of pooled averages that ignore massive internal contradictions. This study reports high I2 for all-cause dementia ranging from 81.5% to 93%, which is a red flag. This number indicates that the studies being combined […]
Comment: This UK Biobank cohort study highlights a conflict between the narrative of statins as a vascular panacea and the documented reality that their use is associated with a 19% increased risk of incident Alzheimer’s disease (HR = 1.19). Looking carefully at the “protective” finding in APOE ε 4 homozygotes (HR = 0.72), there are […]
Comment: Although this study uses perception of sleep versus measured metrics and could suffer from recall bias, I tend to trust people’s perception of how well they sleep, and this one shows significant improvements with sexual activity. Gender differences in sleep perception exist for partnered sex alone, however these disparities effectively vanish if an orgasm […]
Comment: This genotype study once again contradicts the prevailing narrative that meat is a universal cognitive toxin, and even it’s negative impact on all-cause mortality. The findings from this 15-year Swedish cohort are unequivocal. There is absolutely no genetic subgroup in this study where higher total meat consumption increased the risk of dementia. In fact, […]
Comment: This observational MESA study highlights the stark conflict between the idea that early HRT initiation saves lives and the more likely textbook manifestation of healthy user bias impacting outcomes of medical efficacy. Unfortunately the study does not have the data on the formulation used (oral, topical, vaginal), however given the time of intake (2000-2002), […]
Comment: With all testing of secondary markers it’s always important to remember that there’s never a straight line correlation. I don’t care about cholesterol – I care about cardiovascular events. And similarly a patient does not suffer from a low T-score; they suffer from a fracture. Evaluating fracture risk within this systematic review there is […]
Comment: I incorporate high-sensitivity CRP into every cardiovascular workup because it captures a physiological reality that standard lipid panels miss. As this foundational paper details, hsCRP identifies high-risk individuals—even those with low cholesterol—who are otherwise invisible to standard screening algorithms. It is an unfortunate reality that markers are frequently ignored because there is no FDA-approved […]
Comment: The traditional clinical focus on a generic “meat-cancer link” ignores the underlying reality that preserved meats and fresh red meats are entirely different biological entities. While the IARC Working Group found sufficient evidence for processed meat as a Group 1 carcinogen—linked to the formation of N-nitroso compounds (NOCs)—the evidence for fresh red meat remains […]