Comment: This is a crucial systematic review that directly addresses a common clinical misconception. For years, the standard advice has been to stop fish oil before surgery due to a theoretical risk of bleeding based on its known effects on platelet aggregation. What this review clearly demonstrates is that this theoretical risk does not […]
Comment: This study is a critical piece of evidence that directly challenges a long-standing piece of medical dogma. For decades, we have routinely advised patients to stop fish oil supplements before surgery, fearing an increased risk of bleeding. This was solely based on hypothesis. This robust analysis of the OPERA trial not only debunks that […]
Comment: comment here Summary: Clinical Bottom Line This large-scale, pooled analysis of observational studies provides moderate-quality evidence that higher levels of omega-3 fatty acids from habitual dietary intake are not associated with an increased risk of atrial fibrillation (AF) and may, in fact, be modestly protective. Specifically, while eicosapentaenoic acid (EPA) levels showed no association, […]
Comment: Summary: Clinical Bottom Line This review presents a compelling “double-edged sword” hypothesis for the effect of omega-3 fatty acids on the risk of atrial fibrillation (AF). The key takeaway is that the dose and source matter. Low-to-moderate dietary intake of omega-3s from fish (around 600–700 mg/day) appears to be associated with a reduced […]
Comment: Although this doesn’t negate the potential of increased risk of atrial fibrillation seen in other studies, a lower rate of death seems more important. Summary: Clinical Bottom Line This large cohort study shows a modest association between habitual fish oil use and a lower risk of all-cause mortality. However, it is not possible to […]
Comment: This article made a big splash in the media and led to a lot of questions from patients about the safety of taking fish oil supplements. Understanding that this is an observational study, it does show an increase in atrial fibrillation in people who consume fish oil supplements. What’s intriguing, and makes me more […]
