Comment: While this is an observational study and cannot prove causation, the findings are nonetheless concerning, especially as it’s not the only study showing an association of levothyroxine use and cancer. A nation-wide study identifying a 24% increase in the odds of breast cancer associated with levothyroxine use (AOR 1.24) warrants serious attention from the […]
Comment: This is an important, large-scale population study, even with the weaknesses of the study design. An adjusted odds ratio of 1.50 for any cancer is a significant signal that cannot be easily dismissed, particularly given the strong associations noted for brain (AOR 1.90) and breast (AOR 1.24) cancers. While the authors rightly point out […]
Comment: The traditional thinking is that estrogen provides a protective buffer for the aging cardiovascular system. However, this meta-analysis of 33 randomized controlled trials dismantles that assumption, identifying an 86% increased risk of venous thromboembolism and a 23% increased risk of stroke. We must stop viewing these hormones through the narrow lens of symptom suppression […]
