Diet & Nutrition – Page 2 – NatWonk – Dr Bier's Research Reviews

Meal Skipping and Shorter Meal Intervals Are Associated with Increased Risk of All-Cause and Cardiovascular Disease Mortality among US Adults

January 24, 2026

| Cardiovascular Health, Diet & Nutrition, Longevity & Mortality

Comment: There is a conflict between the biochemical promise of Time-Restricted Eating (TRE) and the hard reality of epidemiological survival data. Protocols like “One Meal a Day” (OMAD) are promoted for their theoretical impact on autophagy and insulin sensitivity, yet frequently ignores the most important metric: Overall Survival. While short-term mechanistic studies suggest metabolic benefit, […]

Breakfast skipping and risk of all-cause, cardiovascular and cancer mortality among adults: a systematic review and meta-analysis of prospective cohort studies

January 24, 2026

| No Comments

| Cancer, Cardiovascular Health, Diet & Nutrition, Longevity & Mortality

Comment: The data presented in this systematic review and meta-analysis of 242,095 participants reveals a stark collision between the biochemical promise of intermittent fasting (IF) and the hard reality of epidemiological survival. While IF is frequently promoted as a metabolic panacea—citing mechanisms like autophagy and improved insulin sensitivity—these theories often ignore the hierarchy of harm: […]

Effect of Soy Isoflavones on Measures of Estrogenicity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

December 27, 2025

| No Comments

| Cancer, Diet & Nutrition

Comment: This systematic review and meta-analysis is yet another high-level confirmation of a reality seen across decades of human clinical data: soy isoflavones do not possess the systemic estrogenic risks often attributed to them. In the hierarchy of research, human RCTs carry the most weight, and the aggregation of 42 randomized controlled trials here should […]

Coffee drinking timing and mortality in US adults

December 21, 2025

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| Diet & Nutrition, Longevity & Mortality

🍵Comment: Another study dismantling the dogma that coffee is ‘bad for you.’ On the contrary, the data here shows that ‘morning-type’ drinkers enjoy a statistically significant reduction in both all-cause and cardiovascular mortality compared to non-drinkers. These findings also introduce a vital caveat: the circadian context. The fact that heavy consumption is protective only in […]

Association of Skipping Breakfast with Metabolic Syndrome and Its Components: A Systematic Review and Meta-Analysis of Observational Studies

October 24, 2025

| No Comments

| Cardiovascular Health, Diet & Nutrition, Metabolic Health

Comment: I am in general not a fan of intermittent fasting as my experience is it puts the body in a state of stress, which may give short term gains, but longer term negative outcomes. This is a study showing that skipping breakfast increases metabolic syndrome, including blood sugar, blood pressure, blood lipids and central […]

Animal and plant protein usual intakes are not adversely associated with all-cause, cardiovascular disease-, or cancer-related mortality risk: an NHANES III analysis

September 20, 2025

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| Cancer, Cardiovascular Health, Diet & Nutrition, Longevity & Mortality

Comment: Another study showing that animal protein intake does not increase death rates. In fact, this study links higher animal protein intake to a reduced risk of cancer, albeit small. This study was designed specifically to revisit the controversial 2014 Levine findings that suggested a four-fold cancer risk from animal protein. By applying more sophisticated statistical […]