Comment: This analysis of 17 prospective cohorts demonstrates that higher circulating levels of DHA and DPA are associated with a significant reduction in incident atrial fibrillation, effectively rebutting the idea that Omega-3s are universally pro-arrhythmic. The tangible significance of this data is that it provides a clear signal that dietary fish consumption and physiological levels […]
Comment: This review presents a biologically plausible mechanism for why we see such divergent outcomes between dietary omega-3 intake and high-dose pharmacological interventions. While low-to-moderate physiological levels can be antiarrhythmic, the massive dosing used in synthetic pharmaceutical trials may cross a threshold into proarrhythmic territory. The actual clinical utility of this data is the recognition […]
Comment: Although this doesn’t negate the potential of increased risk of atrial fibrillation seen in other studies, a lower rate of death seems more important. Summary: Clinical Bottom Line This large cohort study shows a modest association between habitual fish oil use and a lower risk of all-cause mortality. However, it is not possible to […]
Comment: This article made a big splash in the media and led to a lot of questions from patients about the safety of taking fish oil supplements. Understanding that this is an observational study, it does show an increase in atrial fibrillation in people who consume fish oil supplements. What’s intriguing, and makes me more […]
Comment: The traditional thinking is that estrogen provides a protective buffer for the aging cardiovascular system. However, this meta-analysis of 33 randomized controlled trials dismantles that assumption, identifying an 86% increased risk of venous thromboembolism and a 23% increased risk of stroke. We must stop viewing these hormones through the narrow lens of symptom suppression […]
Comment: Another study showing that animal protein intake does not increase death rates. In fact, this study links higher animal protein intake to a reduced risk of cancer, albeit small. This study was designed specifically to revisit the controversial 2014 Levine findings that suggested a four-fold cancer risk from animal protein. By applying more sophisticated statistical […]
